Nerve block rebound pain mystery probed in healthy volunteers

NCT ID NCT06005480

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at why some people feel a sharp increase in pain when a numbing injection (nerve block) wears off after surgery. Researchers gave 40 healthy adults a nerve block in one arm and measured pain sensitivity as the block faded. The goal was to understand if the block itself causes temporary extra sensitivity, which could help improve pain management after surgery.

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Conditions

The condition(s) this trial relates to.

Acute Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

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