Nerve block aftermath: study probes mysterious rebound pain
NCT ID NCT06005480
First seen Nov 05, 2025 · Last updated May 08, 2026 · Updated 21 times
Summary
This study looked at why some people feel a sharp increase in pain after a local anesthetic (numbing shot) wears off, a phenomenon called rebound pain. Forty healthy volunteers received a nerve block in one arm and had their pain sensitivity measured as the block faded. The goal was to see if the nerve block itself makes the area more sensitive to pain temporarily.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
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