Could sex explain why sleep apnea harms women's hearts more?

NCT ID NCT04436731

First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time

Summary

This study investigates whether sex and obesity influence how blood vessels respond to low oxygen levels, a key factor in sleep apnea. Researchers will compare healthy-weight and obese men and women to see if differences in vessel constriction and dilation help explain why women with sleep apnea face higher cardiovascular risks. The goal is to uncover mechanisms that could lead to better, sex-specific therapies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this research could point toward better treatments for cardiovascular disease in people with sleep apnea, especially tailored by sex.
What could go wrong
This is an early-stage observational study, not a treatment trial. Findings may not lead directly to new therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Aneurysm Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Missouri-Columbia

    Columbia, Missouri, 65211, United States

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