Liver function may change how this drug works – new study recruiting

NCT ID NCT07219550

First seen Jun 27, 2026 · Last updated Aug 05, 2026 · Updated 2 times

Summary

This study looks at how the drug MK-1084 (calderasib) moves through the body in people with and without liver problems. Researchers will measure drug levels in the blood and check for side effects. About 58 adults will take a single dose and be monitored. The goal is to understand if liver impairment changes how the drug is processed, which helps doctors decide on safe dosing.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Arizona Clinical Trials ( Site 0003)

    Chandler, Arizona, 85225, United States

  • Orlando Clinical Research Center ( Site 0001)

    Orlando, Florida, 32809, United States

  • The Texas Liver Institute ( Site 0002)

    San Antonio, Texas, 78215, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.