Which ear zap feels best? scientists test two waveforms for vagus nerve stimulation
NCT ID NCT06614933
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested how different electrical waveforms (biphasic vs. monophasic) affect comfort and tolerability of transcutaneous auricular vagus nerve stimulation (taVNS) in 30 healthy adults. Participants received one hour of stimulation while reporting discomfort and heart rate changes. The goal is to identify the most tolerable waveform for future therapeutic applications.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
transcutaneous auricular vagus nerve stimulation (taVNS) device
What this could lead to
If successful, this could help design more comfortable taVNS protocols for future therapeutic use.
What could go wrong
This is a small, early-stage study in healthy volunteers, so results may not apply to patient populations or predict long-term tolerability.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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University of Miami, Plumer Building
Coral Gables, Florida, 33146, United States