Which ear zap feels best? scientists test two waveforms for vagus nerve stimulation
NCT ID NCT06614933
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested how different electrical waveforms (biphasic vs. monophasic) affect comfort and tolerability of transcutaneous auricular vagus nerve stimulation (taVNS) in 30 healthy adults. Participants received one hour of stimulation while reporting discomfort and heart rate changes. The goal is to identify the most tolerable waveform for future therapeutic applications.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- transcutaneous auricular vagus nerve stimulation (taVNS) device
- What this could lead to
- If successful, this could help design more comfortable taVNS protocols for future therapeutic use.
- What could go wrong
- This is a small, early-stage study in healthy volunteers, so results may not apply to patient populations or predict long-term tolerability.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Miami, Plumer Building
Coral Gables, Florida, 33146, United States
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