Drug interaction study: does itraconazole change how BI 706321 works?
NCT ID NCT04714073
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This completed Phase 1 trial studied 14 healthy men to see how itraconazole, a common antifungal, affects the levels of a new experimental drug called BI 706321 in the body. Participants took BI 706321 alone and then again after several days of itraconazole. The goal was to measure how the body absorbs and processes the drug, which helps guide future dosing recommendations.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
BI 706321 and itraconazole
What this could lead to
If successful, this study will help determine the right dosing for BI 706321 when taken with other medications.
What could go wrong
This is a very early, small study in healthy volunteers, not patients. It only looks at drug levels, not whether the drug works for any disease.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HEALTHY are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
CRS Clinical Research Services Mannheim GmbH
Mannheim, 68167, Germany