Drug interaction study: does itraconazole change how BI 706321 works?
NCT ID NCT04714073
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This completed Phase 1 trial studied 14 healthy men to see how itraconazole, a common antifungal, affects the levels of a new experimental drug called BI 706321 in the body. Participants took BI 706321 alone and then again after several days of itraconazole. The goal was to measure how the body absorbs and processes the drug, which helps guide future dosing recommendations.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- BI 706321 and itraconazole
- What this could lead to
- If successful, this study will help determine the right dosing for BI 706321 when taken with other medications.
- What could go wrong
- This is a very early, small study in healthy volunteers, not patients. It only looks at drug levels, not whether the drug works for any disease.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HEALTHY are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CRS Clinical Research Services Mannheim GmbH
Mannheim, 68167, Germany
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a new oral drug change future treatments? early safety trial begins
- Can brain scans unlock the secret to hearing in crowded rooms?
- Can a Light-Guided device make arterial sticks easier?
- Water workouts could be the key to back pain relief
- Could everyday disinfectants be harming us? a new study investigates
- Can a new drug keep the Heart's beat steady? trial puts verducatib to the test