M.d. Anderson Cancer Center

This study tests a combination of four chemotherapy drugs (cladribine, idarubicin, cytarabine, and venetoclax) in people with acute myeloid leukemia, high-risk myelodysplastic syndrome, or a fast-growing form of chronic myeloid leukemia. The goal is to see how well these drugs ki…

This study follows patients who receive radiofrequency ablation (RFA), a minimally invasive heat treatment, for benign thyroid nodules or low-risk thyroid cancers. Researchers aim to track the long-term effectiveness of RFA and learn more about patients' quality of life after the…

This study is testing whether adding focused radiation after surgery or laser heat therapy helps control recurrent brain metastases better than surgery/laser therapy alone. Researchers will compare two approaches: one group gets additional radiation after their procedure, while t…

This study compares two topical cream treatments for people with multiple actinic keratoses, which are rough, scaly skin patches that can turn into skin cancer. Researchers want to see if adding calcipotriene cream to the standard fluorouracil cream works better at clearing these…

This study is testing whether a combination of three drugs—pembrolizumab, carboplatin, and paclitaxel—can effectively shrink tumors in people with early-stage triple-negative breast cancer before they have surgery. The goal is to see if this approach can completely eliminate canc…

This study tests a new imaging device called the Active Biopsy Guidance System. It helps doctors decide when and where to take tissue samples (biopsies) from suspicious mouth lesions. The goal is to see if the device can accurately identify which lesions need a biopsy, potentiall…

This study tests whether the drug canakinumab can prevent lung cancer in 50 people who have suspicious lung nodules that haven't gone away. Participants receive the drug and are monitored for nodule shrinkage, cancer development, and side effects. The goal is to see if this appro…

This study aims to collect leftover fluid and tissue samples from routine lung procedures to create a research bank. The goal is to help scientists better understand and treat lung problems, especially those related to cancer treatments. Participants are adults already scheduled …