New hope for rare blood cancers: targeted drug combo enters human testing
NCT ID NCT06616636
First seen Dec 26, 2025 · Last updated May 15, 2026 · Updated 19 times
Summary
This early-phase study tests a new drug called rezatapopt combined with azacitidine in 24 adults whose acute myeloid leukemia or myelodysplastic syndrome has a specific TP53 gene mutation (Y220C). The main goal is to check safety and side effects. Participants must have cancer that returned or did not respond to prior treatment.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The University of Texas MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Conditions
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