Experimental combo targets rare sarcomas with genetic mutations

NCT ID NCT06308419

First seen Nov 16, 2025 · Last updated Jun 14, 2026 · Updated 22 times

Summary

This early-phase trial aims to find a safe dose of gemcitabine combined with nab-sirolimus for people with advanced leiomyosarcoma or soft-tissue sarcoma that has specific TSC1 or TSC2 gene changes. About 18 participants will receive the drug combination to see how well it is tolerated. The goal is to control the disease, not to cure it.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.