Experimental pill SHY-ONC6 takes on Hard-to-Treat cancers
NCT ID NCT07705334
First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time
Summary
This early-stage trial tests an experimental oral drug called SHY-ONC6 in people with advanced or metastatic solid tumors (including breast, colon, lung, pancreatic, and others) that have stopped responding to standard treatments. The study aims to find a safe dose and check for early signs of tumor shrinkage. Participants take the drug once daily in 21-day cycles until their disease worsens or side effects become unacceptable.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- an experimental oral drug called SHY-ONC6
- What this could lead to
- If it works, this could point toward a new treatment option for people with advanced solid tumors who have run out of standard therapies.
- What could go wrong
- This is a very early, first-in-human trial with only 30 participants, so safety and effectiveness are not yet known. Many early-stage cancer drugs do not advance to later trials.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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NEXT Oncology
RECRUITINGSan Antonio, Texas, 78229, United States
Contact
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SCRI at HCA HealthONE
NOT_YET_RECRUITINGDenver, Colorado, 80218, United States
Contact
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The University of Texas MD Anderson Cancer Center
NOT_YET_RECRUITINGHouston, Texas, 77030, United States
Contact
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