Supercharged cord blood cells take on resistant blood cancers

NCT ID NCT07444632

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tests a new type of immune cell therapy for people with several kinds of blood cancers that have come back or stopped responding to treatment. The therapy uses natural killer (NK) cells from donated cord blood, which are genetically modified to better recognize and attack cancer cells while resisting the tumor's attempts to shut them down. Up to 60 participants will receive these cells along with chemotherapy to prepare the body. The main goal is to check safety and side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

engineered natural killer (NK) cells from cord blood, modified to target cancer cells and resist tumor suppression

What this could lead to

If it works, this could point toward a new treatment option for patients with hard-to-treat lymphoid cancers who have run out of standard therapies.

What could go wrong

This is a very early Phase 1 trial with only 60 participants, focused on safety. The approach is experimental, may not work, and could cause serious side effects like immune reactions or organ damage.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

B-cell acute lymphoblastic leukemia B-cell non-Hodgkin lymphoma Hodgkins lymphoma lymphoid system disorder T-cell non-Hodgkin lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The University of Texas M. D. Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact