Could a common drug ease chronic stomach pain and nausea?
NCT ID NCT01696734
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether domperidone, a drug that helps the stomach empty food, can reduce symptoms like pain, bloating, nausea, and vomiting in people with chronic digestive disorders. About 200 patients who have not improved with standard treatments will take domperidone and report their symptom changes over 8 weeks. The goal is to see if the drug can provide relief for conditions such as gastroparesis, severe heartburn, and indigestion.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Domperidone
What this could lead to
If it works, this could provide a treatment option for people with chronic gastrointestinal disorders who have not been helped by standard therapies.
What could go wrong
This is an early-phase trial with only 200 participants, and it focuses on symptom improvement rather than a cure. Domperidone may cause side effects, and its long-term safety is not fully established.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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M D Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-••••
Contact