Could a botox shot in the gut ease Kids' chronic vomiting?

This trial tests whether injecting botulinum toxin into the pylorus—the muscle at the stomach's exit—can help children aged 30 days to 18 years who struggle with chronic nausea, vomiting, or feeding intolerance. Participants receive the injection during an upper endoscopy, and researchers track changes in quality of life and symptom severity over four weeks. The goal is to see if relaxing this muscle improves how well children tolerate feeds and reduces distressing symptoms.