GASTROESOPHAGEAL REFLUX DISEASE

This study compares two types of laparoscopic surgery (Nissen vs. Hill-Snow fundoplication) for children with severe acid reflux. The goal is to see which technique better preserves normal stomach emptying and reduces post-surgery problems like bloating or trouble swallowing. The…

This study tests a modified version of sleeve gastrectomy, a common weight-loss surgery, to see if it can reduce or prevent acid reflux (GERD) that often occurs after the standard procedure. About 44 adults with obesity and GERD will be randomly assigned to receive either the sta…

This trial tests whether a new robotic system that uses only one small incision (single port) can safely perform common abdominal surgeries in children. The study includes children aged 1 to 17 who need procedures like pyeloplasty or reflux treatment. The goal is to see if the si…

This study is testing a new robotic system that uses just one small incision to perform surgeries on the liver, pancreas, stomach, and esophagus. The goal is to see if this single-port approach is safe and works well for these complex operations. The study will enroll 35 adults w…

This study compares two types of surgery for patients with early-stage stomach cancer near the esophagus. One method adds a procedure to widen the stomach outlet, which may help prevent severe acid reflux after surgery. The trial will track reflux, quality of life, and complicati…

This study looks at whether using a biosynthetic mesh during robotic anti-reflux surgery can lower the chance that a hiatal hernia returns. About 200 adults with GERD who are already scheduled for surgery will be randomly assigned to receive either the standard repair or repair w…

This trial tests whether personalized dietary guidance from a nutritionist can reduce symptoms of gastroesophageal reflux disease (GERD) better than a standard educational leaflet. Adults with chronic reflux symptoms will receive either tailored advice or written guidelines, and …

This study tests whether domperidone, a drug that helps the stomach empty food, can reduce symptoms like pain, bloating, nausea, and vomiting in people with chronic digestive disorders. About 200 patients who have not improved with standard treatments will take domperidone and re…

This study looks back at the medical records of about 5,000 Chinese patients with gastroesophageal reflux disease (GERD) to build a detailed picture of their symptoms, treatments, and quality of life. The goal is to understand how GERD affects people in China and how well differe…

This study looks at whether weak esophageal contractions (ineffective motility) improve after partial fundoplication surgery for gastroesophageal reflux. Researchers will perform high-resolution manometry 18-24 months after surgery in 100 patients who had weak contractions before…