GASTROESOPHAGEAL REFLUX DISEASE
Clinical trials for GASTROESOPHAGEAL REFLUX DISEASE explained in plain language.
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Simple surgical Add-On cuts reflux after gastric sleeve
Disease control CompletedThis study tested whether adding a small repair (crural repair and gastropexy) to standard sleeve gastrectomy surgery could reduce acid reflux in people with severe obesity. Fifty patients were split into two groups: one got the standard surgery, the other got the standard surger…
Matched conditions: GASTROESOPHAGEAL REFLUX DISEASE
Phase: NA • Sponsor: Van Training and Research Hospital • Aim: Disease control
Last updated May 12, 2026 13:42 UTC
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Brain-Targeted pills soothe stubborn heartburn in new study
Symptom relief CompletedThis study tested whether gut-brain neuromodulators (Flupentixol-Melitracen) can improve symptoms in people with gastroesophageal reflux disease (GERD) who still have issues despite standard acid-reducing drugs. 164 adults with GERD took part. The goal was to see if these drugs c…
Matched conditions: GASTROESOPHAGEAL REFLUX DISEASE
Phase: NA • Sponsor: RenJi Hospital • Aim: Symptom relief
Last updated May 17, 2026 03:09 UTC
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New GERD pill shows symptom relief in large study
Symptom relief CompletedThis study looked at how well FEXUCLUE tablets improve symptoms like heartburn and acid reflux in people with erosive gastroesophageal reflux disease (GERD). Over 2,800 adults took the medicine for 4 to 8 weeks and reported their symptom changes. The goal was to see if the drug h…
Matched conditions: GASTROESOPHAGEAL REFLUX DISEASE
Sponsor: Daewoong Pharmaceutical Co. LTD. • Aim: Symptom relief
Last updated May 15, 2026 11:53 UTC
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Xiamen study reveals hidden GERD patterns in 1,600+ adults
Knowledge-focused CompletedThis study aimed to find out how common gastroesophageal reflux disease (GERD) is in Xiamen, China, and what factors increase the risk. Researchers surveyed and examined 1,625 adults who had typical reflux symptoms like heartburn. The goal was to better understand the disease's i…
Matched conditions: GASTROESOPHAGEAL REFLUX DISEASE
Sponsor: Zhongshan Hospital (Xiamen), Fudan University • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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Why Aren't we screening for this cancer? new study investigates
Knowledge-focused CompletedThis study surveyed over 700 doctors and patients to find out why people at risk for Barrett's esophagus (a condition that can lead to esophageal cancer) don't get screened. The goal is to identify barriers and improve screening rates. No treatments were tested.
Matched conditions: GASTROESOPHAGEAL REFLUX DISEASE
Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated May 07, 2026 18:43 UTC
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Constipation drugs may reveal new clues about gut health in Barrett's esophagus patients
Knowledge-focused CompletedThis early study looked at whether two FDA-approved constipation drugs, plecanatide and linaclotide, change levels of a chemical called cGMP in the small intestine. Researchers compared tissue samples from 43 adults with Barrett esophagus or GERD who took one of the drugs or no d…
Matched conditions: GASTROESOPHAGEAL REFLUX DISEASE
Phase: PHASE1 • Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated May 06, 2026 16:02 UTC