Can surgery offer lasting relief for chronic heartburn? a large registry investigates
NCT ID NCT02923362
First seen Aug 07, 2026 · Last updated Aug 07, 2026
Summary
This registry follows thousands of adults who undergo laparoscopic surgery for gastroesophageal reflux disease (GERD) or hiatal hernia. It compares two common procedures: fundoplication, which wraps part of the stomach around the esophagus to reinforce the valve, and the LINX device, a magnetic ring that helps keep acid from backing up. The goal is to see how patients' quality of life changes after surgery and whether one approach offers better long-term outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Laparoscopic fundoplication (a surgical procedure that wraps the top of the stomach around the lower esophagus to strengthen the valve) and the LINX device (a magnetic ring implanted around the esophagus to help keep stomach acid from flowing back up).
- What this could lead to
- If successful, this registry could clarify which surgical approach offers better long-term quality of life for people with chronic acid reflux or hiatal hernia, helping guide treatment decisions.
- What could go wrong
- As a registry, it does not randomly assign treatments, so comparisons may be biased. Surgery carries risks like difficulty swallowing, bloating, or recurrence of symptoms, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Advanced Surgeons, PC
Birmingham, Alabama, 35243, United States
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Affinity Medical Group
Chilton, Wisconsin, 53014, United States
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Bass Medical Group
Walnut Creek, California, 94598, United States
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Baylor Scott and White Research Institute
Dallas, Texas, 75204, United States
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Baylor University Medical Center at Dallas
Dallas, Texas, 75246, United States
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Coastal Carolina Bariatric and Surgical Center
Summerville, South Carolina, 29485, United States
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Froedtert & The Medical College of Wisconsin Hospitals and Health Partners
Milwaukee, Wisconsin, 53226, United States
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HealthOne Cardiothoracic Surgery Associates
Aurora, Colorado, 80012, United States
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Houston Methodist Research Institute
Houston, Texas, 77030, United States
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Institute of Esophageal and Reflux Surgery
Englewood, Colorado, 80113, United States
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Mayo Clinic
Jacksonville, Florida, 32224, United States
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North Texas Surgical Oncology Associates
Plano, Texas, 75075, United States
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South Florida Surgical Specialists, LLC
Coral Springs, Florida, 33065, United States
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Suncoast Surgical Associates
Brandon, Florida, 33511, United States
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Swedish Health Services
Seattle, Washington, 98103, United States
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Tampa Bay Reflux Center
Riverview, Florida, 33578, United States
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The Arkansas Heartburn Treatment Center
Heber Springs, Arkansas, 72543, United States
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The Tampa Bay Reflux Center
Tampa, Florida, 33609, United States
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University of Southern Alabama
Mobile, Alabama, 36617, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a tailored diet quiet the burn of acid reflux?
- Can big data unlock better GERD treatment for chinese patients?
- Which Anti-Reflux surgery is kinder to a Child's stomach?
- Single-Port robot could make pediatric surgery less invasive
- Mindfulness app may soothe heartburn and anxiety in GERD patients
- Unnecessary test? study questions routine throat tube before reflux surgery