Crushed or whole? tiny study tests Pill-Swallowing workaround for cGVHD drug

NCT ID NCT07127926

Recruiting now Disease control Sponsor: M.D. Anderson Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether crushing belumosudil tablets and mixing them with water changes how the drug is absorbed in people with chronic graft-versus-host disease (cGVHD). Only 8 participants who have had a stem cell transplant will take the drug both ways and have their blood levels measured. The goal is to see if crushing is a safe option for those who have trouble swallowing whole tablets.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: belumosudil
What this could lead to: If successful, this could show that crushing belumosudil tablets is a safe and effective option for patients who have trouble swallowing whole pills.
What could go wrong: This is a very small study (8 people) and only looks at short-term drug levels, not long-term outcomes. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CHRONIC GRAFT VERSUS HOST DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Bronchiolitis Obliterans Syndrome chronic graft versus host disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC GRAFT VERSUS HOST DISEASE

Contacts and locations

Locations

The University of Texas M. D. Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.