Crushed or whole? tiny study tests Pill-Swallowing workaround for cGVHD drug

NCT ID NCT07127926

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether crushing belumosudil tablets and mixing them with water changes how the drug is absorbed in people with chronic graft-versus-host disease (cGVHD). Only 8 participants who have had a stem cell transplant will take the drug both ways and have their blood levels measured. The goal is to see if crushing is a safe option for those who have trouble swallowing whole tablets.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

belumosudil

What this could lead to

If successful, this could show that crushing belumosudil tablets is a safe and effective option for patients who have trouble swallowing whole pills.

What could go wrong

This is a very small study (8 people) and only looks at short-term drug levels, not long-term outcomes. Results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Bronchiolitis Obliterans Syndrome chronic graft versus host disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The University of Texas M. D. Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact