New hope for teens with chronic Graft-Versus-Host disease: belumosudil under study

NCT ID NCT06616415

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested the drug belumosudil in Chinese teenagers aged 12 to 18 with chronic graft-versus-host disease (cGVHD), a complication after stem cell transplant. The goal was to see how well the drug works and how safe it is for those who didn't respond to steroids. Six participants took a tablet once daily, and researchers measured drug levels, response rates, and side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

belumosudil (a drug taken as a tablet to treat chronic graft-versus-host disease)

What this could lead to

If it works, this could offer a new treatment option for teenagers with chronic graft-versus-host disease who haven't improved with steroids.

What could go wrong

This is a very small study (only 6 participants) and is already completed, so results may not apply to all patients. The drug may not work better than existing treatments or could cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CHRONIC GRAFT-VERSUS-HOST-DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Bronchiolitis Obliterans Syndrome chronic graft versus host disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Investigational Site Number : 1560001

    Beijing, 100045, China

  • Investigational Site Number : 1560002

    Shanghai, 200127, China