Double antiviral attack: could two flu drugs beat one for vulnerable patients?
NCT ID NCT04712539
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial tests whether combining two antiviral drugs, baloxavir and oseltamivir, works better than oseltamivir alone for severe flu in people with weakened immune systems (such as blood cancer patients or stem cell transplant recipients). The study will measure how quickly the virus clears and whether the combination reduces hospital stays or complications. 60 participants are being recruited at MD Anderson Cancer Center.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Baloxavir marboxil and oseltamivir
What this could lead to
If it works, this combination could offer a more effective treatment for severe flu in people with weakened immune systems, reducing hospital stays and complications.
What could go wrong
This is a small, early-phase trial (60 participants) in a very specific group (cancer or transplant patients). The combination may not work better than oseltamivir alone, and there is a risk of side effects or drug resistance.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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M D Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact