Can a simple breath test catch flu in High-HIV regions?

NCT ID NCT07030075

Recruiting now Knowledge-focused Sponsor: Centre for Infectious Disease Research in Zambia Source: ClinicalTrials.gov ↗

First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time

Summary

This study in Lusaka, Zambia, aims to measure how common influenza, RSV, and COVID-19 are among adults with flu-like symptoms, comparing those with and without HIV. Researchers will follow participants for two weeks to track symptom progression and outcomes. They will also test whether a breath-based sampling method can accurately detect these viruses compared to standard nasal swabs, and ask participants about their experience with each method.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Exhaled breath aerosol sampling (a non-invasive diagnostic method)
What this could lead to: If successful, this could improve flu diagnosis in high-HIV settings and support faster, more acceptable testing for respiratory infections.
What could go wrong: This is an observational study, so it won't test a treatment. The breath sampling method may not be as accurate as standard swabs, and results may not apply beyond this specific population.

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Conditions

The condition(s) this trial relates to.

COVID-19 influenza respiratory syncytial virus infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COVID-19 INFLUENZA RSV

Contacts and locations

Locations

Chawama 1st level Hospital
RECRUITING

Lusaka, Lusaka Province, 10101, Zambia
Kanyama 1st Level Hospital
RECRUITING

Lusaka, Lusaka Province, 10101, Zambia

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