New hope for tough colorectal cancer: Triple-Drug attack

NCT ID NCT06369259

First seen Feb 14, 2026 · Last updated May 16, 2026 · Updated 14 times

Summary

This study tests whether a combination of three drugs—avutometinib, defactinib, and cetuximab—can help control advanced colorectal cancer that has stopped responding to standard treatments. About 33 adults with unresectable, anti-EGFR-refractory cancer will receive the drugs and be monitored for safety and side effects. The goal is to find a new way to manage the disease when other options have failed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77807, United States

    Contact Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.