Can a new drug combo shrink Hard-to-Treat colorectal tumors?

This trial is testing whether an experimental drug called MRG007, given together with standard chemotherapy and targeted therapies, can safely shrink tumors in people with advanced colorectal cancer that cannot be removed by surgery. The study involves about 316 participants and will look at side effects, how the drug moves through the body, and whether it helps control the disease. The goal is to find a dose that works well enough to test further.