New drug combo aims to outperform standard therapy for advanced colorectal cancer

NCT ID NCT07676162

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This phase 3 trial tests whether adding the experimental drug SHR-A1811 to standard chemotherapy and bevacizumab works better than standard therapy alone for people with advanced colorectal cancer who have not had prior treatment. About 300 participants will receive either the new combination or the standard regimen. The study measures how long the cancer stays under control and whether tumors shrink.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SHR-A1811

What this could lead to

If successful, this could offer a more effective first-line treatment option for people with advanced colorectal cancer, potentially slowing disease progression.

What could go wrong

This is an early-phase 3 trial, and the experimental drug may not prove more effective than standard therapy. Side effects from combining multiple drugs could be significant.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal adenocarcinoma colorectal cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing cancer Hospital

    Beijing, Beijing Municipality, 100142, China

    Contact