ADVANCED COLORECTAL CANCER
Clinical trials for ADVANCED COLORECTAL CANCER explained in plain language.
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New hope for tough colorectal cancer: Triple-Drug attack
Disease control Recruiting nowThis study tests whether a combination of three drugs—avutometinib, defactinib, and cetuximab—can help control advanced colorectal cancer that has stopped responding to standard treatments. About 33 adults with unresectable, anti-EGFR-refractory cancer will receive the drugs and …
Matched conditions: ADVANCED COLORECTAL CANCER
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 17, 2026 01:47 UTC
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New drug cocktail shows promise against tough rectal cancer
Disease control Recruiting nowThis study tests a mix of three drugs (irinotecan liposome, capecitabine, and enlansubemab) given alongside a short course of radiation before surgery for locally advanced rectal cancer. The goal is to see if this combination can make tumors disappear completely before surgery. A…
Matched conditions: ADVANCED COLORECTAL CANCER
Phase: PHASE2 • Sponsor: Tianjin Medical University Cancer Institute and Hospital • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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New hope for hard-to-treat bowel cancer: combo therapy enters phase 2 trial
Disease control Recruiting nowThis study tests a new drug called TL938 combined with trastuzumab in people with HER2-positive colorectal cancer that has spread or come back and cannot be removed by surgery. About 80 adults who have already tried standard treatments will receive the combination to find the bes…
Matched conditions: ADVANCED COLORECTAL CANCER
Phase: PHASE2 • Sponsor: Suzhou Teligene Ltd. • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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New hope for Hard-to-Treat colorectal cancer: first human trial launches
Disease control Recruiting nowThis early-stage study tests a new drug called CBI-1214 in people with advanced colorectal cancer that has not responded to standard treatments. The drug works by helping the body's immune cells attack cancer cells. The main goals are to check safety and find the best dose, while…
Matched conditions: ADVANCED COLORECTAL CANCER
Phase: PHASE1 • Sponsor: Cartography Biosciences • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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New combo therapy aims to control advanced colorectal cancer
Disease control Recruiting nowThis study tests a new first-line treatment for people with advanced colorectal cancer that cannot be removed by surgery or has spread. The treatment combines two drugs, levozolinate and 5-FU, given together through an IV. The goal is to see if this approach helps control the can…
Matched conditions: ADVANCED COLORECTAL CANCER
Phase: PHASE2 • Sponsor: Chinese PLA General Hospital • Aim: Disease control
Last updated May 13, 2026 16:03 UTC
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New pill targets common cancer driver in advanced tumors
Disease control Recruiting nowThis early-phase study tests a new experimental drug called BGB-53038 in people with advanced or metastatic solid tumors that have a specific genetic change (KRAS mutation or amplification). The drug is a pan-KRAS inhibitor, meaning it aims to block many forms of the faulty KRAS …
Matched conditions: ADVANCED COLORECTAL CANCER
Phase: PHASE1 • Sponsor: BeiGene • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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New drug aims to rev up immune system against tough colon cancer
Disease control Recruiting nowThis study tests an experimental drug called RBS2418 in 150 adults with advanced colorectal cancer that has spread and is no longer responding to standard treatments. The drug works by helping the immune system recognize and attack cancer cells. Participants will receive either R…
Matched conditions: ADVANCED COLORECTAL CANCER
Phase: PHASE2 • Sponsor: Riboscience, LLC. • Aim: Disease control
Last updated May 01, 2026 15:57 UTC
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Blood test may help colorectal cancer patients keep quality of life longer
Knowledge-focused Recruiting nowThis study is testing whether using a blood test (liquid biopsy) to monitor treatment response can help people with advanced colorectal cancer maintain a better quality of life for longer. About 150 adults starting their first treatment for metastatic colorectal cancer will be ra…
Matched conditions: ADVANCED COLORECTAL CANCER
Phase: PHASE3 • Sponsor: University Hospital, Antwerp • Aim: Knowledge-focused
Last updated May 13, 2026 16:00 UTC