Mini tumors in a dish could pick the right drug for stubborn cancers
NCT ID NCT05267912
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether growing a patient's tumor cells in the lab (as 3D 'organoids') can help doctors pick the best drug for advanced cancers that have stopped responding to standard treatments. About 152 adults with colorectal or pancreatic cancer will have a biopsy to create these organoids, which are then exposed to a panel of drugs to see which ones work. The goal is to see if this personalized approach is feasible and can improve how long patients live without their cancer growing.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
tumor organoid-based chemogram (lab test on biopsy sample)
What this could lead to
If successful, this could help doctors choose more effective drugs for patients with advanced cancers that have stopped responding to standard treatments.
What could go wrong
This is an early feasibility study, not a treatment trial. The organoid test may not always predict real patient responses, and results may not lead to better outcomes for everyone.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CHU de Poitiers
NOT_YET_RECRUITINGPoitiers, France, 86000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Centre Eugène Marquis
RECRUITINGRennes, France, 35000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Centre Léon Bérard
ACTIVE_NOT_RECRUITINGLyon, France, 69008, France
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Centre Oscar Lambret
RECRUITINGLille, France, 59000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Gustave Roussy
RECRUITINGVillejuif, 94805, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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HIA Bégin
RECRUITINGSaint-Mandé, France, 94160, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital Pitié-Salpêtrière
RECRUITINGParis, France, 75013, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital Saint Louis
RECRUITINGParis, France, 75010, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital St Antoine
RECRUITINGParis, France, 75571, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Institut Bergonié
RECRUITINGBordeaux, France, 33000, France
Contact Email: •••••@•••••
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Institut Godinot
RECRUITINGReims, France, 51726, France
Contact Phone: •••-•••-•••• Email: •••••@•••••