New hope for stubborn gut cancers? early trial launches

NCT ID NCT07216560

Recruiting now Disease control Sponsor: Mabwell (Shanghai) Bioscience Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase trial is testing an experimental drug called 7MW4911 in 200 people with advanced colorectal or other gastrointestinal cancers that have progressed after standard treatments. The main goals are to find a safe dose and to see if the drug can shrink tumors. It is the first time this drug is being studied in humans in the US.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 7MW4911 (an experimental drug)
What this could lead to: If it works, this could point toward a new treatment option for people with advanced gastrointestinal cancers that have stopped responding to standard therapies.
What could go wrong: This is a very early first-in-human study, so the drug may not work or could cause unexpected side effects. The results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

colorectal cancer digestive system cancer digestive system neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GI CANCERS

Contacts and locations

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Locations

Fred Hutchinson Cancer Center
RECRUITING

Seattle, Washington, 98109, United States
Hematology Oncology Associates of the Treasure Coast
RECRUITING

Port Saint Lucie, Florida, 34952, United States
Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States
START
RECRUITING

Long Island City, New York, 11042, United States
START Moutain Region
RECRUITING

West Valley City, Utah, 84119, United States

Contact Email: •••••@•••••

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