New hope for stubborn gut cancers? early trial launches

NCT ID NCT07216560

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase trial is testing an experimental drug called 7MW4911 in 200 people with advanced colorectal or other gastrointestinal cancers that have progressed after standard treatments. The main goals are to find a safe dose and to see if the drug can shrink tumors. It is the first time this drug is being studied in humans in the US.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

7MW4911 (an experimental drug)

What this could lead to

If it works, this could point toward a new treatment option for people with advanced gastrointestinal cancers that have stopped responding to standard therapies.

What could go wrong

This is a very early first-in-human study, so the drug may not work or could cause unexpected side effects. The results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal cancer digestive system cancer digestive system neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Fred Hutchinson Cancer Center

    RECRUITING

    Seattle, Washington, 98109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hematology Oncology Associates of the Treasure Coast

    RECRUITING

    Port Saint Lucie, Florida, 34952, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • START

    RECRUITING

    Long Island City, New York, 11042, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • START Moutain Region

    RECRUITING

    West Valley City, Utah, 84119, United States

    Contact Phone: •••-•••-••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••