ADVANCED COLORECTAL CANCER
Clinical trials for ADVANCED COLORECTAL CANCER explained in plain language.
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New targeted combo aims to outsmart Hard-to-Treat colorectal cancer
Disease control OngoingThis phase 3 trial tests whether a new targeted drug (MRTX849) combined with cetuximab works better than standard chemotherapy for people with advanced colorectal cancer that has a specific KRAS G12C mutation. About 461 participants whose cancer worsened after first-line treatmen…
Matched conditions: ADVANCED COLORECTAL CANCER
Phase: PHASE3 • Sponsor: Mirati Therapeutics Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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New hope for hard-to-treat cancers: targeted combo shows promise
Disease control OngoingThis study tests a new drug (JAB-21822) combined with cetuximab in people with advanced colorectal, small intestine, or appendiceal cancers that have a specific KRAS G12C mutation. Participants must have already tried at least one standard treatment. The goal is to see if the com…
Matched conditions: ADVANCED COLORECTAL CANCER
Phase: PHASE1, PHASE2 • Sponsor: Allist Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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New injection could spare cancer patients from repeated belly drains
Symptom relief OngoingThis Phase 3 trial tests a drug called M701, given as an injection into the belly, to see if it can reduce the need for draining fluid in people with malignant ascites from advanced stomach, colorectal, or ovarian cancer. About 312 participants will either receive M701 plus drain…
Matched conditions: ADVANCED COLORECTAL CANCER
Phase: PHASE3 • Sponsor: Wuhan YZY Biopharma Co., Ltd. • Aim: Symptom relief
Last updated Jun 27, 2026 12:32 UTC
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Stool test or scope? study seeks best way to monitor hidden colon cancer risk
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at people aged 45-74 who had a positive fecal immunochemical test (FIT) but a normal colonoscopy. Even with a clear colonoscopy, these individuals may still have a higher risk of colorectal cancer. The trial will compare two follow-up options after two years: ano…
Matched conditions: ADVANCED COLORECTAL CANCER
Sponsor: National Taiwan University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC