ADVANCED COLORECTAL CANCER
Clinical trials for ADVANCED COLORECTAL CANCER explained in plain language.
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New hope for hard-to-treat colorectal cancer: targeted combo enters phase 3
Disease control OngoingThis study tests whether a new drug (MRTX849) combined with cetuximab works better than standard chemotherapy for people with advanced colorectal cancer that has a specific genetic change called KRAS G12C. About 461 participants whose cancer worsened after first treatment will be…
Matched conditions: ADVANCED COLORECTAL CANCER
Phase: PHASE3 • Sponsor: Mirati Therapeutics Inc. • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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New drug combo targets tough cancers with KRAS mutation
Disease control OngoingThis study tests a combination of two drugs, JAB-21822 and cetuximab, in people with advanced colorectal, small intestine, or appendiceal cancers that have a specific KRAS G12C mutation. The goal is to see if the combo is safe and can shrink tumors. About 48 adults who have alrea…
Matched conditions: ADVANCED COLORECTAL CANCER
Phase: PHASE1, PHASE2 • Sponsor: Allist Pharmaceuticals, Inc. • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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Stool test positive, colonoscopy clear: what next? landmark trial seeks answer
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at people aged 45-74 who had a positive fecal immunochemical test (FIT) but a normal colonoscopy. Even with a clear colonoscopy, these individuals may still have a higher risk of colorectal cancer later. The trial compares two follow-up strategies after two years…
Matched conditions: ADVANCED COLORECTAL CANCER
Sponsor: National Taiwan University Hospital • Aim: Knowledge-focused
Last updated May 17, 2026 09:18 UTC