New hope for hard-to-treat cancers: targeted combo shows promise
NCT ID NCT05194995
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new drug (JAB-21822) combined with cetuximab in people with advanced colorectal, small intestine, or appendiceal cancers that have a specific KRAS G12C mutation. Participants must have already tried at least one standard treatment. The goal is to see if the combination is safe and can shrink tumors. This is not a cure, but aims to control the disease.
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the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Research site01
Beijing, Beijing Municipality, 100101, China
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Research site02
Beijing, Beijing Municipality, 100101, China
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Research site05
Zhengzhou, Henan, 450000, China
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Research site06
Harbin, Heilongjiang, 150000, China
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Research site07
Zhengzhou, Henan, 450000, China
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Research site08
Nanchang, Jiangxi, 330000, China
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Research site09
Nanjing, Jiangsu, 210000, China
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Research site11
Changsha, Hunan, 410000, China
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Research site12
Beijing, Beijing Municipality, 100101, China
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Research site13
Nanning, Guangxi, 530021, China
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Research site16
Linyi, Shandong, 276002, China
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Research site18
Wuhan, Hubei, 430079, China
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Research site19
Hangzhou, Zhejiang, 310005, China
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Research site23
Xi’an, Shanxi, 710000, China
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Research site28
Shanghai, Shanghai Municipality, 200032, China
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Research site29
Changsha, Hunan, 410000, China
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Research site31
Beijing, Beijing Municipality, 100021, China