New hope for rectal cancer: drug combo plus radiation aims to wipe out tumors before surgery

NCT ID NCT07281157

First seen Jan 04, 2026 · Last updated Jun 07, 2026 · Updated 26 times

Summary

This study is testing a combination of three drugs (liposomal irinotecan, capecitabine, and enlonstobart) plus a short course of radiation before surgery for people with locally advanced rectal cancer. The goal is to see if this approach can make tumors disappear completely or leave no cancer cells behind after surgery. About 30 adults aged 18-75 with stage cT3-4 or node-positive rectal cancer will take part. The study is currently recruiting.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Tianjin Medical University Cancer Institute & Hospital

    RECRUITING

    Tianjin, Tianjin Municipality, 300000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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