New drug RBS2418 aims to rev up immune system against tough colorectal cancer
NCT ID NCT06824064
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 2a trial tests an experimental drug called RBS2418 in 150 adults with advanced, metastatic colorectal cancer that has worsened despite standard treatments. The drug is designed to help the immune system recognize and attack cancer cells. Participants will receive either RBS2418 or a placebo, alongside best supportive care, to see if the drug can slow tumor growth and improve survival.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
RBS2418
What this could lead to
If it works, this could offer a new treatment option for people with advanced colorectal cancer who have run out of standard therapies.
What could go wrong
This is an early Phase 2a trial with only 150 participants, so results may not confirm benefit. The drug may not slow tumor growth or could cause side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Christiana Care
RECRUITINGNewark, Delaware, 19718, United States
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Community Clinical Trials
RECRUITINGKingwood, Texas, 77339, United States
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Pan Oncology
RECRUITINGSan Juan, 00935, Puerto Rico
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Tam Anh TP. Ho Chi Minh General Hospital
RECRUITINGHo Chi Minh City, Ho Chi Minh City, 70000, Vietnam
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Tam Anh, Ha Noi General Hospital
RECRUITINGHà Nội, 10000, Vietnam