Blood test may spot returning colorectal cancer earlier

NCT ID NCT04739072

Recruiting now Knowledge-focused Sponsor: M.D. Anderson Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing if a simple blood test can find tiny bits of tumor DNA left after treatment, which might help doctors know if colorectal cancer will return sooner than current methods. About 1,000 people with colorectal cancer who have finished or are about to start treatment will give blood samples over time. The goal is to see if these DNA signals can predict recurrence and improve follow-up care.

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Conditions

The condition(s) this trial relates to.

colorectal adenocarcinoma colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLORECTAL ADENOCARCINOMA STAGE I COLORECTAL CANCER AJCC V8 STAGE II COLORECTAL CANCER AJCC V8 STAGE IIA COLORECTAL CANCER AJCC V8 STAGE IIB COLORECTAL CANCER AJCC V8 STAGE IIC COLORECTAL CANCER AJCC V8 STAGE III COLORECTAL CANCER AJCC V8 STAGE IIIA COLORECTAL CANCER AJCC V8 STAGE IIIB COLORECTAL CANCER AJCC V8 STAGE IIIC COLORECTAL CANCER AJCC V8 STAGE IV COLORECTAL CANCER AJCC V6 STAGE IVA COLORECTAL CANCER AJCC V8 STAGE IVB COLORECTAL CANCER AJCC V8 STAGE IVC COLORECTAL CANCER AJCC V8

Contacts and locations

Locations

Banner - MD Anderson Cancer Center
TERMINATED

Gilbert, Arizona, 85234, United States
Baptist- MD Anderson Cancer Center
TERMINATED

Jacksonville, Florida, 32207, United States
Baylor Scott & White Research Institute
TERMINATED

Temple, Texas, 76508, United States
Cooper Hospital UNIV MED CTR.
TERMINATED

Camden, New Jersey, 08103, United States
Houston Methodist Cancer Center
TERMINATED

Houston, Texas, 77030, United States
M D Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
St. Luke's Cancer Institute
TERMINATED

Boise, Idaho, 83712, United States
The Queen's Medical Center
TERMINATED

Honolulu, Hawaii, 96813, United States
UT Health San Antonio MD Anderson Cancer Center
TERMINATED

San Antonio, Texas, 78229, United States
UT Southwestern/Simmons Cancer Center-Dallas
TERMINATED

Dallas, Texas, 75390, United States

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