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New drug hope for Tough-to-Treat colorectal cancer

NCT ID NCT06959550

Recruiting now Disease control Sponsor: M.D. Anderson Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a drug called ivonescimab in 90 adults with advanced colorectal cancer that has already been treated. The drug is designed to help the immune system fight the cancer. Researchers want to see if it is safe and can control the disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Ivonescimab
What this could lead to
If it works, this could point toward a new treatment option for people with advanced colorectal cancer that hasn't responded to prior therapy.
What could go wrong
This is an early Phase 2 study with only 90 participants, so results may not apply to everyone. The drug may cause side effects or fail to control the cancer.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

METASTATIC COLORECTAL CANCER

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • The University of Texas M. D. Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Email: •••••@•••••

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