Rice-Sized implant could personalize sarcoma treatment

NCT ID NCT04199026

Recruiting now Knowledge-focused Sponsor: M.D. Anderson Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Aug 12, 2026 · Updated 3 times

Summary

This early trial tests a rice-sized microdevice implanted into sarcoma tumors. The device releases tiny doses of up to 10 different drugs to see which ones kill cancer cells. The goal is to check if the device is safe and can help choose the best treatment for each patient. The study involves 20 people with recurrent or metastatic sarcoma who are already scheduled for surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: microdevice loaded with multiple drugs (including doxorubicin)
What this could lead to: If successful, this could lead to a way to test which drugs work best for each patient's sarcoma before full treatment.
What could go wrong: This is a very early pilot trial with only 20 people. The device may not work as expected, and results may not apply to all sarcomas.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

METASTATIC SARCOMA RECURRENT SARCOMA RESECTABLE SARCOMA

Contacts and locations

Locations

M D Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States

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