Radiation beams take aim at spreading sarcoma in young patients

NCT ID NCT06796543

Recruiting now Disease control Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 14, 2026 · Updated 3 times

Summary

This study tests whether giving targeted radiation to cancer that has spread (metastasized) can help children, teens, and young adults with sarcoma live longer. About 70 participants with soft tissue or bone sarcoma will receive consolidative radiation therapy to their metastatic spots. The goal is to see if this approach improves survival compared to past outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: consolidative radiation therapy
What this could lead to: If it works, this could improve survival rates for young patients with sarcoma that has spread to a few spots in the body.
What could go wrong: This is a small, early-phase study without a control group, so results may not be definitive. Radiation also has side effects like fatigue and skin irritation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bone sarcoma brain cancer Ewing sarcoma rhabdomyosarcoma sarcoma soft tissue sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EWING SARCOMA METASTATIC SARCOMA RADIATION THERAPY PATIENT RHABDOMYOSARCOMA

Contacts and locations

Locations

Johns Hopkins Hospital
RECRUITING

Baltimore, Maryland, 21287, United States
Sibley Memorial Hospital
RECRUITING

Washington D.C., District of Columbia, 20016, United States
University of Minnesota
RECRUITING

Minneapolis, Minnesota, 55455, United States

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