New PET tracer could sharpen sarcoma detection
NCT ID NCT04457258
First seen Jul 17, 2026 · Last updated Jul 17, 2026
Summary
This early-phase trial tests a radioactive tracer called 68Ga-FAPI-46 to see where it collects in the body of people with sarcoma. Participants receive the tracer and undergo a PET/CT scan, which combines a detailed anatomical image (CT) with a functional image (PET) that highlights areas where the tracer accumulates. The goal is to understand how well this tracer binds to sarcoma tumors compared to normal tissues, and to confirm these findings by comparing scan results with tissue samples from surgery or biopsy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a radioactive tracer called 68Ga-FAPI-46, given intravenously, used with PET/CT imaging
- What this could lead to
- If successful, this imaging technique could help doctors better detect and monitor sarcoma, potentially guiding treatment decisions.
- What could go wrong
- This is a very early, small study (18 people) focused on imaging, not treatment. The tracer may not clearly distinguish cancer from normal tissue, and results may not apply to other cancers.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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UCLA / Jonsson Comprehensive Cancer Center
Los Angeles, California, 90095, United States
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