New inhaled MRI tracer could spot lung damage before it happens
NCT ID NCT06909201
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether a special MRI scan using an inhaled gas called hyperpolarized xenon-129 can help doctors identify and predict lung damage caused by radiation therapy in lung cancer patients. The gas is breathed in instead of being injected like a typical contrast dye. The study will include 70 people: some healthy volunteers and some lung cancer patients receiving radiation. The main goal is to see if the scan is safe and can detect early signs of lung injury.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Hyperpolarized Xenon-129 (inhaled gas tracer for MRI)
- What this could lead to
- If successful, this imaging method could help doctors predict and reduce lung damage from radiation therapy, improving quality of life for lung cancer patients.
- What could go wrong
- This is an early, small study focused on imaging, not treatment. The tracer is not FDA-approved, and the main goal is safety and feasibility, not proving clinical benefit.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The University of Texas M. D. Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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