New drug combo aims to control rare ovarian cancer

NCT ID NCT06065462

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether combining two drugs, dostarlimab and LB-100, can help control ovarian clear cell carcinoma. About 21 adults with recurrent disease will receive the drugs by vein. The main goal is to check safety and see if the tumors shrink or stop growing.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

dostarlimab and LB-100

What this could lead to

If it works, this combination could offer a new treatment option for ovarian clear cell carcinoma, helping to control the disease.

What could go wrong

This is an early phase 1/2 trial with only 21 participants, so results are preliminary. The drugs may cause side effects and may not effectively control the cancer.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OVARIAN CLEAR CELL CARCINOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

ovarian clear cell cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••