HIV drug shows promise against Hard-to-Treat vulvar cancer

NCT ID NCT04169763

First seen Nov 01, 2025 · Last updated Apr 24, 2026 · Updated 21 times

Summary

This early-phase study tests whether adding the HIV drug nelfinavir to standard chemotherapy (cisplatin) and radiation can safely treat locally advanced vulvar cancer that cannot be surgically removed. About 25 adults with stage II–IVA vulvar cancer will receive different doses of nelfinavir alongside cisplatin and daily radiation. The main goal is to find the best dose and check for side effects, while also tracking how long the cancer stays under control.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-••••

    Contact

Conditions

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