Blood test may help cancer patients avoid nerve damage from chemo

NCT ID NCT03987555

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 4 times

Summary

This pilot study aims to see if doctors can consistently measure paclitaxel levels in the blood of cancer patients receiving the drug. The goal is to eventually adjust doses to give enough chemo to fight cancer while reducing the common side effect of nerve damage. The study involves 22 adults with various solid tumors and uses blood draws and surveys to track drug exposure and symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
paclitaxel
What this could lead to
If successful, this could help doctors adjust paclitaxel doses to reduce nerve damage while still effectively treating cancer.
What could go wrong
This is a small, early feasibility study with only 22 participants and is currently suspended. It focuses on whether blood monitoring is practical, not on proving it improves outcomes.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Wake Forest Baptist Comprehensive Cancer Center

    Winston-Salem, North Carolina, 27157, United States

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