3D-Printed mouth guards could ease radiation side effects for cancer patients
NCT ID NCT04870762
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether custom 3D-printed oral stents can reduce mouth sores in head and neck cancer patients receiving radiation therapy. The stents are made from a mold of the patient's mouth and cover teeth and gums during treatment. Researchers will compare sore rates and patient-reported symptoms between those who use the stent and those who receive standard care alone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
customized 3D-printed oral stent
What this could lead to
If it works, this could provide a simple, non-drug way to reduce painful mouth sores during radiation therapy for head and neck cancer.
What could go wrong
This is a mid-stage trial with only 119 participants, so results may not apply to everyone. The stent may not fit all patients or significantly reduce sores compared to standard care.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Banner Health/Banner Research
RECRUITINGPhoenix, Arizona, 85234, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Baptist MD Anderson Cancer Center
RECRUITINGJacksonville, Florida, 32207, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Community MD Anderson Cancer Center East
RECRUITINGIndianapolis, Indiana, 46219, United States
Contact Email: •••••@•••••
Contact
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Community MD Anderson Cancer Center North
RECRUITINGIndianapolis, Indiana, 46250, United States
Contact Email: •••••@•••••
Contact
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Community MD Anderson Cancer Center South
RECRUITINGIndianapolis, Indiana, 46227, United States
Contact Email: •••••@•••••
Contact
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Cooper Hospital University Medical Center
RECRUITINGCamden, New Jersey, 08103, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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M D Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact