New combo cream could shorten treatment for Sun-Damaged skin
NCT ID NCT06851507
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding calcipotriene to the standard cream fluorouracil works better for people with multiple actinic keratoses (precancerous skin spots). Thirty adults will apply either fluorouracil alone for 2-3 weeks or a combination cream for just 4 days. Researchers will compare side effects and how well each treatment clears the spots.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- fluorouracil and calcipotriene creams
- What this could lead to
- If it works, this could point toward a shorter, more effective treatment for actinic keratoses, reducing the number of precancerous spots.
- What could go wrong
- This is a small pilot study with only 30 participants, so results may not apply to everyone. The combination cream might cause more skin irritation or side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The University of Texas M. D. Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States