New combo cream could shorten treatment for Sun-Damaged skin

NCT ID NCT06851507

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding calcipotriene to the standard cream fluorouracil works better for people with multiple actinic keratoses (precancerous skin spots). Thirty adults will apply either fluorouracil alone for 2-3 weeks or a combination cream for just 4 days. Researchers will compare side effects and how well each treatment clears the spots.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

fluorouracil and calcipotriene creams

What this could lead to

If it works, this could point toward a shorter, more effective treatment for actinic keratoses, reducing the number of precancerous spots.

What could go wrong

This is a small pilot study with only 30 participants, so results may not apply to everyone. The combination cream might cause more skin irritation or side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

actinic keratosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The University of Texas M. D. Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact