Radiation boost may keep melanoma at bay for immunotherapy patients

NCT ID NCT04594187

Recruiting now Disease control Sponsor: M.D. Anderson Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 11, 2026 · Updated 2 times

Summary

This study looks at whether giving radiation to the lymph nodes after surgery can lower the chance of melanoma returning in people who are already receiving immunotherapy. About 168 adults with high-risk melanoma that has spread to a sentinel lymph node will take part. The goal is to see if adding radiation reduces the risk of cancer coming back in the same area.

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Conditions

The condition(s) this trial relates to.

melanoma metastatic melanoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MELANOMA

Contacts and locations

Locations

Baptist - MD Anderson Cancer Center
RECRUITING

Jacksonville, Florida, 32207, United States
Cooper Hospital UNIV MED CTR.
RECRUITING

Camden, New Jersey, 08103, United States
M D Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States

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