Experimental drug targets Hard-to-Treat salivary gland cancers

NCT ID NCT05884320

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests whether the drug sacituzumab govitecan can help control salivary gland cancer that has come back or spread to other parts of the body. About 30 adults whose cancer cannot be removed by surgery or cured with radiation will receive the drug through an IV. Researchers will monitor side effects and how well the drug works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

sacituzumab govitecan (a drug given by IV)

What this could lead to

If it works, this could offer a new treatment option for people with salivary gland cancer that has come back or spread.

What could go wrong

This is a small, early-phase trial with only 30 participants, so results may not apply to everyone. The drug can cause side effects like nausea, fatigue, and low blood cell counts.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

adenocarcinoma adenoid cystic carcinoma mucoepidermoid carcinoma salivary duct carcinoma salivary gland cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact