Can esophageal cancer patients still fight pneumonia after radiation?

NCT ID NCT06181656

Recruiting now Knowledge-focused Sponsor: M.D. Anderson Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how radiation treatment for esophageal cancer affects the body's ability to respond to the pneumonia vaccine. Researchers will give the vaccine to 80 patients who have low white blood cell counts after chemoradiation. They want to see if the vaccine still works well enough to protect against pneumonia.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Pneumonia vaccine
What this could lead to: If successful, this could help doctors understand how to better protect esophageal cancer patients from pneumonia after radiation treatment.
What could go wrong: This is a small, early-stage observational study, not a treatment trial. It may not lead to any changes in care, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

esophageal cancer Esophageal Neoplasms liver cancer lymphopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHEMORADIATION ESOPHAGEAL CANCER LYMPHOPENIA PNEUMOCOCCAL VACCINE

Contacts and locations

Locations

MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States

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