Engineered immune cells take on rare sarcomas in early trial

NCT ID NCT06083883

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 31 times

Summary

This early-phase study tests a new treatment for people with advanced synovial sarcoma or myxoid/round cell liposarcoma. Participants receive donated immune cells (NK cells) that are engineered to recognize a protein called NY-ESO-1 on cancer cells, along with chemotherapy to prepare the body. The main goal is to find a safe dose and check for side effects. About 44 adults with specific genetic markers are being enrolled.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.