Cold virus engineered to attack brain tumors shows promise in early trial

NCT ID NCT03896568

First seen Nov 01, 2025 · Last updated Jun 11, 2026 · Updated 32 times

Summary

This early-phase trial tests a new approach for people with recurrent high-grade glioma, an aggressive brain cancer. Researchers use a modified cold virus (DNX-2401) loaded into stem cells and injected into an artery to target and attack tumor cells. The main goals are to find the safest dose and understand side effects in 36 participants.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-••••

    Contact

Conditions

Explore the condition pages connected to this study.