New drug duo targets brain metastases in HER2-Positive cancers

NCT ID NCT05673928

First seen Jan 24, 2026 · Last updated May 30, 2026 · Updated 21 times

Summary

This study tests whether two drugs, tucatinib and T-DM1, can control HER2-positive solid tumors that have spread to the brain. About 30 adults with this condition will receive the combination treatment. The main goal is to see how safe and tolerable the drugs are, and whether they can shrink or stabilize brain tumors.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.