Heated chemo during surgery shows promise for tough ovarian cancer
NCT ID NCT05123807
First seen Nov 01, 2025 · Last updated Jun 21, 2026 · Updated 27 times
Summary
This phase 2 trial tests whether combining surgery to remove visible tumor with heated chemotherapy delivered directly into the abdomen can help women whose mucinous ovarian cancer has returned. About 30 participants will receive this intensive treatment. The goal is to see how long they live without the cancer growing again and overall survival.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
hyperthermic intraperitoneal chemotherapy (HIPEC)
What this could lead to
If successful, this approach could offer a new treatment option to control recurrent mucinous ovarian cancer and potentially extend survival.
What could go wrong
This is a small, early-phase trial with only 30 participants, so results may not apply to all patients. The combination of major surgery and heated chemotherapy carries risks like infection, organ damage, and complications from anesthesia.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.