New MRI scan could predict jaw bone damage in cancer patients

NCT ID NCT03145077

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a special type of MRI (called DCE-MRI) can predict jaw bone damage (osteoradionecrosis) in head and neck cancer patients who have had radiation therapy. Researchers will scan up to 1,400 participants before, during, and after radiation to see if changes in the jaw bone and soft tissue can be detected early. The goal is to find a way to identify patients at risk for this serious side effect before it happens.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI)

What this could lead to

If successful, this could help doctors predict and prevent jaw bone damage in head and neck cancer patients receiving radiation therapy.

What could go wrong

This is an observational study, not a treatment trial. It may not lead to a direct benefit for participants, and the MRI technique might not prove accurate enough for routine use.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms osteoradionecrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact