Stitch showdown: can a simple change prevent hernias after liver surgery?

NCT ID NCT04982653

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This trial tests whether a different way of closing the abdominal wall during liver tumor surgery can lower the chance of developing an incisional hernia. 140 patients will be randomly assigned to receive either the new 'short stitch' method or the traditional closure. Researchers will track hernia rates using scans at 3, 6, and 12 months after surgery.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
surgical closure technique (short stitch suture vs. traditional suture)
What this could lead to
If successful, this could establish a simple change in surgical stitching that reduces the risk of incisional hernias after liver surgery.
What could go wrong
This is a Phase 2 trial with 140 patients, so results may not apply to all surgeries. The benefit may be small or not statistically significant.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

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