New chemo cocktail aims to fight childhood germ cell tumors that return
NCT ID NCT07662018
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how well a combination of four chemotherapy drugs (gemcitabine, docetaxel, melphalan, and carboplatin) followed by a stem cell transplant works in children and teens up to age 21 whose germ cell tumors have come back or not responded to treatment. Researchers will track side effects and treatment outcomes in about 30 participants. The goal is to gather information that could help improve care for this hard-to-treat cancer.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- gemcitabine, docetaxel, melphalan, carboplatin
- What this could lead to
- If successful, this combination could offer a treatment option for children whose germ cell tumors have returned or not responded to standard therapy.
- What could go wrong
- This is an observational study with a small group of 30 participants, so results may not apply broadly. The chemotherapy regimen carries risks of serious side effects, including infection and organ damage.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CARBOPLATIN are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- New transplant strategy shows promise for blood cancer relapse
- Healing harmonies: music therapy aims to ease stem cell transplant recovery
- Muscle stem cell study ends early — but may pave way for future treatments
- New chemo combo could improve outcomes for stomach cancer patients
- New hope for kids with tough leukemias: experimental combo trial opens
- Could white blood cells boost cord transplants for tough leukemia?